In the words of the European Commission, ‘EU Missions are a new way to bring concrete solutions to some of our greatest challenges. They will deliver impact by putting research and innovation into a new role, combined with new forms of governance and collaboration, as well as by engaging citizens. They also aim to mobilise public and private actors, such as EU Member States, regional and local authorities, research institutes, farmers and land managers, entrepreneurs and investors to create real and lasting impact. Missions will engage with citizens to boost societal uptake of new solutions and approaches. EU Missions will support Europe’s transformation into a greener, healthier, more inclusive and resilient continent.’ In T-Factor, we leverage the ‘meanwhile’ in urban regeneration as a collective, laboratorial space to address place-based missions of innovation that are relevant to broader regeneration challenges and to Sustainable Development Goals (SDGs). These missions are designed so as to respond to pressing local problems, and convene a variety of local actors in the pursuit of solutions, pooling material and immaterial resources that are distributed in our cities yet often disconnected. Core to this approach is the understanding of temporary uses as the opportunity to define shared goals of urban regeneration, aligning public and private interests around the creation of shared public value.